| Biomarker ID | 463 |
| PMID | 19542190 |
| Year | 2009 |
| Biomarker | Vascular Endothelial Growth Factor (VEGF) |
| Biomarker Basis | Concentration Based (pg/ml) |
| Biomolecule | Protein |
| Source | Serum |
| Subjects | Humans |
| Regulation | Downregulated after Polyphenon E treatment(9.9%) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-S1P/S1P3 pathway,VEGFR1 pathway, Heart development,Actions of nitric oxide in the heart,Fibroblast growth factor 1 |
| Experiment | Before Vs After Polyphenon E treatment |
| Type of Biomarker | Predictive |
| Cohort | Twenty-six men with positive prostate biopsies, scheduled for radical prostatectomy were given daily doses of Polyphenon E, to detect the affect of the drug. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.032 |
| Method Used | ELISA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | VEGFA |