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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID462
PMID19542190
Year2009
BiomarkerHepatocyte Growth Factor (HGF)
Biomarker BasisConcentration Based (pg/ml)
BiomoleculeProtein
SourceSerum
SubjectsHumans
RegulationDownregulated after Polyphenon E treatment(18.9%)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- Malaria,Response to elevated platelet cytosolic calcium, Melanoma,Syndecan 1 pathway,Signaling events mediated by hepatocyte growth factor receptor (c-Met)
ExperimentBefore Vs After Polyphenon E treatment
Type of BiomarkerPredictive
CohortTwenty-six men with positive prostate biopsies, scheduled for radical prostatectomy were given daily doses of Polyphenon E, to detect the affect of the drug.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.001
Method UsedELISA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameHGF