| Biomarker ID | 46 |
| PMID | 14982837 |
| Year | 2004 |
| Biomarker | alpha-Methylacyl Coenzyme A Racemase (AMACR) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in PCa (Prostate Cancer: 3.14 Vs Benign Prostate: 1.3) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-Primary bile acid biosynthesis,Bile acids and bile salt biosynthesis,Peroxisomal lipid metabolism,Bile acid and bile salt biosynthesis via 7-alpha-hydroxycholesterol,Bile acid and bile salt metabolism |
| Experiment | Benign Prostate Vs Localised Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | 48 benign tissues with 66 clinically localised prostate cancer were selected for analysis |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.00001 |
| Method Used | Immunohistochemistry |
| Clinical | No |
| Remarks | Evaluated on Both Immunohistochemistry and AQUA. Found significant results for both |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | AMACR |