Biomarker ID | 46 |
PMID | 14982837 |
Year | 2004 |
Biomarker | alpha-Methylacyl Coenzyme A Racemase (AMACR) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa (Prostate Cancer: 3.14 Vs Benign Prostate: 1.3) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Primary bile acid biosynthesis,Bile acids and bile salt biosynthesis,Peroxisomal lipid metabolism,Bile acid and bile salt biosynthesis via 7-alpha-hydroxycholesterol,Bile acid and bile salt metabolism |
Experiment | Benign Prostate Vs Localised Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | 48 benign tissues with 66 clinically localised prostate cancer were selected for analysis |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.00001 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | Evaluated on Both Immunohistochemistry and AQUA. Found significant results for both |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | AMACR |