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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID458
PMID19775154
Year2009
BiomarkerProstate specific antigen (PSA), Prostate Specific Membrane Antigen (PSMA), Platelet Factor-4 (PF-4), and Interleukin-6 (IL-6)
Biomarker BasisConcentration Based (ng/mL)
BiomoleculeProtein
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include(KLK3):- ID regulation of gene expression, Prostate cancer,Androgen receptor proteolysis and transcription regulation,Androgen receptor signaling, proteolysis, and transcription regulation,Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs)
ExperimentProstate Cancer Vs Female Controls
Type of BiomarkerDiagnostic
Cohort14 people were chosen for the study. 10 males diagnosed with prostate cancer, and 4 cancer free Females.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of SignificanceNA
Method Usedsingle-wall carbon nanotubes immunoarrays
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameKLK3, FOLH1, PF4, IL6