Biomarker ID | 458 |
PMID | 19775154 |
Year | 2009 |
Biomarker | Prostate specific antigen (PSA), Prostate Specific Membrane Antigen (PSMA), Platelet Factor-4 (PF-4), and Interleukin-6 (IL-6) |
Biomarker Basis | Concentration Based (ng/mL) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include(KLK3):- ID regulation of gene expression, Prostate cancer,Androgen receptor proteolysis and transcription regulation,Androgen receptor signaling, proteolysis, and transcription regulation,Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs) |
Experiment | Prostate Cancer Vs Female Controls |
Type of Biomarker | Diagnostic |
Cohort | 14 people were chosen for the study. 10 males diagnosed with prostate cancer, and 4 cancer free Females. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | NA |
Method Used | single-wall carbon nanotubes immunoarrays |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | KLK3, FOLH1, PF4, IL6 |