| Biomarker ID | 445 |
| PMID | 19489685 |
| Year | 2009 |
| Biomarker | Urinary PSA |
| Biomarker Basis | Concentration Based (pg/μl) |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Upregulated |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include:-ID regulation of gene expression,Prostate cancer,Androgen receptor proteolysis and transcription regulation,Androgen receptor signaling, proteolysis, and transcription regulation,Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs) |
| Experiment | Benign prostatic hyperplasia (BPH) Vs prostate cancer (PCa) |
| Type of Biomarker | Diagnostic |
| Cohort | 96 age matched patients, 26 with BPH and 70 with Prostate Cancer were included for the study |
| Senstivity | 56% |
| Specificity | 100% |
| AUC | 0.771 95% CI: (0.674–0.850) |
| Accuracy | 97.14 95% CI: (85.1–99.9) |
| Level Of Significance | p=0.0001 |
| Method Used | RT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | KLK3 |