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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID444
PMID19489685
Year2009
BiomarkerDifferential display 3 (DD3/PCA3)
Biomarker BasisConcentration Based (pg/μl)
BiomoleculemRNA
SourceUrine
SubjectsHumans
RegulationUpregulated in PCa (37 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentBenign prostatic hyperplasia (BPH) Vs prostate cancer (PCa)
Type of BiomarkerDiagnostic
Cohort96 age matched patients, 26 with BPH and 70 with Prostate Cancer were included for the study
Senstivity60%
Specificity100%
AUC0.814 95% CI: (0.721–0.886)
Accuracy70.83 95% CI: (47.8–88.7)
Level Of Significancep=0.0001
Method UsedRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamePCA3