Biomarker ID | 444 |
PMID | 19489685 |
Year | 2009 |
Biomarker | Differential display 3 (DD3/PCA3) |
Biomarker Basis | Concentration Based (pg/μl) |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated in PCa (37 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Benign prostatic hyperplasia (BPH) Vs prostate cancer (PCa) |
Type of Biomarker | Diagnostic |
Cohort | 96 age matched patients, 26 with BPH and 70 with Prostate Cancer were included for the study |
Senstivity | 60% |
Specificity | 100% |
AUC | 0.814 95% CI: (0.721–0.886) |
Accuracy | 70.83 95% CI: (47.8–88.7) |
Level Of Significance | p=0.0001 |
Method Used | RT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | PCA3 |