Biomarker ID | 441 |
PMID | 19293807 |
Year | 2009 |
Biomarker | Ki-67 |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Differentially Expressed [Cause Specific Survial (Δχ2 = 24.6) and overall survival (Δχ2 = 20.5)] |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 1.06 (95% CI:1.05 -1.07) |
Effect on Pathways | Pathways Include:- RANKL regulation of apoptosis and immune response |
Experiment | Overall Survival Vs No Survival |
Type of Biomarker | Prognostic |
Cohort | Cohort of 808 patients diagnosed with prostate cancer treated conservatively was included in the study, |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | MKI67 |