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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID435
PMID19242826
Year2010
BiomarkerKLK11
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated (CS: (1-2) 6.05 ± 1.34 vs CS 3: 3.93 ± 0.45)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- Collagen chain trimerization, MSP-RON Signaling
ExperimentClincal Stage (1-2) Vs Clinical Stage 3
Type of BiomarkerPrognostic
CohortOut of 63 patients, 39 had Clinical stages (1-2) and 24 had Stage 3.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.009
Method UsedqRT-PCR
ClinicalNo
RemarksResults were then normalized using the ratio of TMPRSS2/ b-actin and KLK11/b-actin concentration for each sample
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameKLK11