| Biomarker ID | 434 |
| PMID | 19242826 |
| Year | 2010 |
| Biomarker | KLK11 |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in PCa: (Normal: 0.49 ± 0.07 vs PCa: 3.63 ± 0.42) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Collagen chain trimerization, MSP-RON Signaling |
| Experiment | prostate cancer Vs Adjacent Normal |
| Type of Biomarker | Diagnostic |
| Cohort | 63 patients with Prostate Cancer were chosen for this study. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.003 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | Results were then normalized using the ratio of TMPRSS2/ b-actin and KLK11/b-actin concentration for each sample |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | KLK11 |