| Biomarker ID | 433 |
| PMID | 19242826 |
| Year | 2010 |
| Biomarker | TMPRSS2 |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated (Tumor Grade 1-2: 2.35 ± 1.45 vs Tumor Grade 3: 3.41 ± 2.31) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Androgen receptor regulation of biosynthesis and transcription,Androgen receptor proteolysis and transcription regulation |
| Experiment | Tumor Grade (1-2) Vs Tumor Grade 3 |
| Type of Biomarker | Prognostic |
| Cohort | Out of 63 patients, 38 had Tumor Grade (1-2) and 25 had Tumor Grade 3. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.016 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | Results were then normalized using the ratio of TMPRSS2/ b-actin and KLK11/b-actin concentration for each sample |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | TMPRSS2 |