| Biomarker ID | 424 |
| PMID | 19229851 |
| Year | 2009 |
| Biomarker | Urokinase-type plasminogen activator receptor (uPAR) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Increased Expression with Biochemical Recurrence |
| Odds Ratio/Hazard Ratio/Relative Risk | Univariate: HR: 1.56 |
| Effect on Pathways | Pathways Include:-Beta-3 integrin cell surface interactions,Dissolution of fibrin clot,Post-translational modification: biosynthesis of GPI-anchored proteins, Urokinase-type plasminogen activator (uPA) and uPAR-mediated signalingIntegrin beta-5 pathway |
| Experiment | Recurrence Vs No recurrence for 5 years |
| Type of Biomarker | Prognostic |
| Cohort | A cohort of 423 men was used to develop and internally validate the post-operative nomogram for prediction of Biochemical Recurrance. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | Concordance Index = 86.3% |
| Level Of Significance | p<0.001 |
| Method Used | enzyme immunoassays |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | PLAUR |