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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID422
PMID19229851
Year2009
BiomarkerEndoglin
Biomarker BasisExpression Based
BiomoleculeProtein
SourcePlasma
SubjectsHumans
RegulationIncreased Expression with Biochemical Recurrence
Odds Ratio/Hazard Ratio/Relative RiskUnivariate: HR: 1.05
Effect on PathwaysPathways Include:-ALK1 pathway,HIF-1 transcriptional activity in hypoxia, TGF-beta signaling pathway
ExperimentRecurrence Vs No recurrence for 5 years
Type of BiomarkerPrognostic
CohortA cohort of 423 men was used to develop and internally validate the post-operative nomogram for prediction of Biochemical Recurrance.
SenstivityNA
SpecificityNA
AUCNA
AccuracyConcordance Index = 86.2%
Level Of Significancep<0.001
Method Usedenzyme immunoassays
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameENG