Biomarker ID | 422 |
PMID | 19229851 |
Year | 2009 |
Biomarker | Endoglin |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Plasma |
Subjects | Humans |
Regulation | Increased Expression with Biochemical Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | Univariate: HR: 1.05 |
Effect on Pathways | Pathways Include:-ALK1 pathway,HIF-1 transcriptional activity in hypoxia, TGF-beta signaling pathway |
Experiment | Recurrence Vs No recurrence for 5 years |
Type of Biomarker | Prognostic |
Cohort | A cohort of 423 men was used to develop and internally validate the post-operative nomogram for prediction of Biochemical Recurrance. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | Concordance Index = 86.2% |
Level Of Significance | p<0.001 |
Method Used | enzyme immunoassays |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | ENG |