Biomarker ID | 421 |
PMID | 19229851 |
Year | 2009 |
Biomarker | Vascular endothelial growth factor (VEGF) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Plasma |
Subjects | Humans |
Regulation | Increased Expression with Biochemical Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | Univariate: HR: 1.01 |
Effect on Pathways | Pathways Include:- S1P/S1P3 pathway,VEGFR1 pathway,Heart development,Actions of nitric oxide in the heart,Fibroblast growth factor 1 |
Experiment | Recurrence Vs No recurrence for 5 years |
Type of Biomarker | Prognostic |
Cohort | A cohort of 423 men was used to develop and internally validate the post-operative nomogram for prediction of Biochemical Recurrance. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | Concordance Index = 86.3% |
Level Of Significance | p=0.002 |
Method Used | enzyme immunoassays |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | VEGFA |