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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID409
PMID19117982
Year2009
BiomarkerAndrogen Receptor AR-V7
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationHigher expression in patients with biochemical recurrence
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways
ExperimentPSA Recurrence Vs No PSA Recurrence
Type of BiomarkerPrognostic
Cohort84 patients diagnosed with Hormone-naive prostate cancer were chosen, along with 25 patients diagnosed with Hormone-Refractory prostate cancer.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.012
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameAR