Biomarker ID | 408 |
PMID | 19117982 |
Year | 2009 |
Biomarker | Androgen Receptor AR-V7 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Hormone Refactory Prostate Cancer (20 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways |
Experiment | Hormone Naive Vs Hormone Refractory Prostate Cancer |
Type of Biomarker | Prognostic |
Cohort | 84 patients diagnosed with Hormone-naive prostate cancer were chosen, along with 25 patients diagnosed with Hormone-Refractory prostate cancer. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.0001 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | AR |