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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID400
PMID19050681
Year2009
BiomarkerKi-67
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- RANKL regulation of apoptosis and immune response
ExperimentLocalized prostate cancer Vs benign prostate
Type of BiomarkerDiagnostic
Cohort82 patients who had undergone radical prostatectomy, matched for pathological stage, Gleason sum score, preoperative PSA, and paired for relapse and non-relapse status. 41 patients with Relapse, and 41 without relapse.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.01
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameMKI67