Biomarker ID | 400 |
PMID | 19050681 |
Year | 2009 |
Biomarker | Ki-67 |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- RANKL regulation of apoptosis and immune response |
Experiment | Localized prostate cancer Vs benign prostate |
Type of Biomarker | Diagnostic |
Cohort | 82 patients who had undergone radical prostatectomy, matched for pathological stage, Gleason sum score, preoperative PSA, and paired for relapse and non-relapse status. 41 patients with Relapse, and 41 without relapse. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.01 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | MKI67 |