| Biomarker ID | 30 |
| PMID | 11926890 |
| Year | 2002 |
| Biomarker | Alpha Methylacyl Coenzyme A Racemase (AMACR) |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in Metastatic Prostate Cancer (1.67 fold) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-Primary bile acid biosynthesis,Bile acids and bile salt biosynthesis,Peroxisomal lipid metabolism,Bile acid and bile salt biosynthesis via 7-alpha-hydroxycholesterol,Bile acid and bile salt metabolism |
| Experiment | Benign Prostate vs Metastatic Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | 57 prostate samples were selected for analysis. 5 were benign Prostatic Tissue, 16 were Benign prostatic hyperplasia (BPH), 16 were Localised Prostate Cancer, and 20 were Metastatic Prostate Cancer. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.004 |
| Method Used | RT-PCR |
| Clinical | No |
| Remarks | Validated on both Protein and RNA level |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | AMACR |