Biomarker ID | 29 |
PMID | 11926890 |
Year | 2002 |
Biomarker | Alpha Methylacyl Coenzyme A Racemase (AMACR) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Localised Prostate Cancer (3.1 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Primary bile acid biosynthesis,Bile acids and bile salt biosynthesis,Peroxisomal lipid metabolism,Bile acid and bile salt biosynthesis via 7-alpha-hydroxycholesterol,Bile acid and bile salt metabolism |
Experiment | Benign Prostate vs Localised Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | 57 prostate samples were selected for analysis. 5 were benign Prostatic Tissue, 16 were Benign prostatic hyperplasia (BPH), 16 were Localised Prostate Cancer, and 20 were Metastatic Prostate Cancer. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | RT-PCR |
Clinical | No |
Remarks | Validated on both Protein and RNA level |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | AMACR |