Biomarker ID | 252 |
PMID | 18336616 |
Year | 2008 |
Biomarker | FOXO1A |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in Gleason Score 7-14 |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- Androgen receptor regulation of biosynthesis and transcription,PI3K cascade,Leptin signaling pathway,Signaling by EGFR in cancer,CXCR4 signaling pathway |
Experiment | Gleason Score 5-6 Vs Gleason Score 7-10 |
Type of Biomarker | Prognostic |
Cohort | 20 patients with Prostate Cancer were included in the study with age matched controls. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | FOXO1 |