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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID252
PMID18336616
Year2008
BiomarkerFOXO1A
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationDownregulated in Gleason Score 7-14
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- Androgen receptor regulation of biosynthesis and transcription,PI3K cascade,Leptin signaling pathway,Signaling by EGFR in cancer,CXCR4 signaling pathway
ExperimentGleason Score 5-6 Vs Gleason Score 7-10
Type of BiomarkerPrognostic
Cohort20 patients with Prostate Cancer were included in the study with age matched controls.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameFOXO1