| Biomarker ID | 251 |
| PMID | 18336616 |
| Year | 2008 |
| Biomarker | PHLPP |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in Gleason Score 7-13 |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Negative regulation of the PI3K/Akt network,NGF signaling via TRKA from the plasma membrane,Signaling by FGFR in disease, Signaling by the B cell receptor (BCR),PI3K events in ERBB2 signaling |
| Experiment | Gleason Score 5-6 Vs Gleason Score 7-10 |
| Type of Biomarker | Prognostic |
| Cohort | 20 patients with Prostate Cancer were included in the study with age matched controls. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | PHLPP1 |