Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 248 |
| PMID | 18336616 |
| Year | 2008 |
| Biomarker | PI3-K p85 α |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in Gleason Score 7-10 |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-Interleukin-3, interleukin-5, and GM-CSF signaling,VEGF, hypoxia, and angiogenesis,Alpha-6 beta-1 and alpha-6 beta-4 integrin signaling,Interleukin-3 signaling pathway,PI3K events in ERBB2 signaling |
| Experiment | Gleason Score 5-6 Vs Gleason Score 7-10 |
| Type of Biomarker | Prognostic |
| Cohort | 20 patients with Prostate Cancer were included in the study with age matched controls. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | PIK3R1 |