Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 245 |
| PMID | 18245462 |
| Year | 2008 |
| Biomarker | PCA3 |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-Proteins Involved in Prostate Cancer |
| Experiment | Normal Vs Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | Total of 234 samples were taken. 138 having prostate cancer (86 positive needle biopsy and 52 radical prostatectomy) and 96 negative biopsy patients. |
| Senstivity | 7540% |
| Specificity | 5630% |
| AUC | 0.661 |
| Accuracy | NA |
| Level Of Significance | p=0.001 |
| Method Used | qPCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | PCA3 |