Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 243 |
| PMID | 18245462 |
| Year | 2008 |
| Biomarker | SPINK1 |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Proteins Involved in Cystic Fibrosis |
| Experiment | Normal Vs Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | Total of 234 samples were taken. 138 having prostate cancer (86 positive needle biopsy and 52 radical prostatectomy) and 96 negative biopsy patients. |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.642 |
| Accuracy | NA |
| Level Of Significance | p=0.0002 |
| Method Used | qPCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | SPINK1 |