Biomarker ID | 241 |
PMID | 18190830 |
Year | 2007 |
Biomarker | Chitotriosidase |
Biomarker Basis | Concentration Based (mmol/ml·h) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa (PCa: 91.33 ± 8.32 Vs BPH: 69.72 ±8.69) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- Amino sugar and nucleotide sugar metabolism,Prolactin regulation of apoptosis |
Experiment | Normal (Control) Vs Cancer (High Gleason Grade) |
Type of Biomarker | Diagnostic |
Cohort | Serum samples from 93 patients with primary prostate cancer, 61 with prostatic hyperplasia, and 56 controls were compared. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | Fluorometer |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | CHIT1 |