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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID231
PMID17460773
Year2007
BiomarkerTSPAN13 + PRKCBP1
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationDifferentially Expressed
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Integrin signaling pathway, TGF-beta regulation of extracellular matrix
ExperimentBenign Prostate Vs Prostate Cancer
Type of BiomarkerDiagnostic
CohortTotal of 56 patients were selected from Stanford Data set and were used for training. Rest of the samples from Stanford Data set, University of Michigan, University of Pittsburg were treated as validation sets.
SenstivityNA
SpecificityNA
AUC0.94 (Stanford); 0.88 (UM); 0.94 (Pittsburg)
AccuracyNA
Level Of Significancep<0.0005
Method UsedNA
ClinicalNo
RemarksResults on Stanford Data Set (Validation Set). Classifier Used:IF (TSPAN13 + PRKCBP1 >= -0.4172 THEN PCA
Clinical Trial NumberNA
Degree Of ValidityValidated on Independent Patient Dataset
Technical NameTSPAN13, ZMYND8