Biomarker ID | 23 |
PMID | 14654526 |
Year | 2003 |
Biomarker | XLKD1/LYVE1+CGA+ F2R/PAR1+ BCL-G |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Differentially Expressed |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include(BCLG):-Mitochondrial pathway of apoptosis: antiapoptotic Bcl-2 family,p53 signaling pathway |
Experiment | Patients with Relapse Vs Without Relapse |
Type of Biomarker | Prognostic |
Cohort | 7 patients with relapse, and 7 without relapse were included in the analysis |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | 100% |
Level Of Significance | p<0.05 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | Out of 291 genes, 46 genes showed differential expression, out of which a 4 gene panel was selected to differentiate b/w the patients who relapsed and those who did not. |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | LYVE1, CGA, F2R, BCLG |