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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID220
PMID17932343
Year2007
BiomarkerVEGF (Vascular Endothelial Growth Factor)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceSerum
SubjectsHumans
RegulationDownregulated in Prostate Cancer
Odds Ratio/Hazard Ratio/Relative RiskOR - 0.89
Effect on PathwaysPathways Include:-S1P/S1P3 pathway, VEGFR1 pathway,Heart development,Actions of nitric oxide in the heart,Fibroblast growth factor 1
ExperimentCancerous Vs Normal Patients
Type of BiomarkerDiagnostic
Cohort123 patients with Prostate Cancer were identified from SABORT cohort and correspondingly 127 age matched cohorts were chosen.
SenstivityNA
SpecificityNA
AUC0.579
AccuracyNA
Level Of Significancep=0.01
Method UsedLabMAP Technology
ClinicalNo
RemarksA total panel of 54 markers was evaluated to check whether they could differentiate between cases (Prostate Cancer) and age matched controls. They panel could not differentiate between the two. But the given markers were found differentially expressed between the two.
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameVEGFA