Biomarker ID | 211 |
PMID | 16618727 |
Year | 2006 |
Biomarker | VCL (Vinculin) [VCL 1534, 0933, 0936] |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Integrins in angiogenesis,Response to elevated platelet cytosolic calcium,Adherens junction cell adhesion, Amoebiasis,Rho cell motility signaling pathway |
Experiment | Cancerous Tissue Vs Normal Tissue |
Type of Biomarker | Diagnostic |
Cohort | Two sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | 0.011744 |
Method Used | RT-PCR and qPCR |
Clinical | No |
Remarks | Brackets indicate ISOFORMS of the mRNA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | VCL |