| Biomarker ID | 207 |
| PMID | 16618727 |
| Year | 2006 |
| Biomarker | IGF1 (Insulin like Growth Factor 1 Somatomedin C) [IGF1 0025] |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Skeletal myogenesis control by HDAC and calcium/calmodulin-dependent kinase (CaMK),BAD phosphorylation regulation,Fibroblast growth factor 1,IGF1 signaling pathway,IGF1 receptor signaling through beta-arrestin |
| Experiment | Cancerous Tissue Vs Normal Tissue |
| Type of Biomarker | Diagnostic |
| Cohort | Two sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | 3.77E-06 |
| Method Used | RT-PCR and qPCR |
| Clinical | No |
| Remarks | Brackets indicate ISOFORMS of the mRNA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | IGF1 |