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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID200
PMID16618727
Year2006
BiomarkerALDH1A2 (Aldehyde Dehydrogenase 1A2) [ALDH1A2 0004,0001, 0006]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationDownregulated
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Vitamin A and carotenoid metabolism,Tryptophan metabolism,Retinol metabolism,Interleukin-4 regulation of apoptosis ,Metabolism
ExperimentCancerous Tissue Vs Normal Tissue
Type of BiomarkerDiagnostic
CohortTwo sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significance0.000266
Method UsedRT-PCR and qPCR
ClinicalNo
RemarksBrackets indicate ISOFORMS of the mRNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameALDH1A2