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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID199
PMID16618727
Year2006
BiomarkerCLU (Clusterin) [CLU 0196, 0192, 0191]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationDownregulated
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Myc repressed pathway,Response to elevated platelet cytosolic calcium,Platelet activation, signaling and aggregation,BDNF signaling pathway,FSH regulation of apoptosis
ExperimentCancerous Tissue Vs Normal Tissue
Type of BiomarkerDiagnostic
CohortTwo sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significance0.000272
Method UsedRT-PCR and qPCR
ClinicalNo
RemarksBrackets indicate ISOFORMS of the mRNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameCLU