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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1936
PMID25786615
Year2013
BiomarkermiR-501-3p
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa [mean PC/mean]: (2.34 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathway include: synapse; Gene expression (Transcription); RNA Polymerase II Transcription; Generic Transcription Pathway; transcription by RNA polymerase II
ExperimentDisseminated PCa VS Localised PCa
Type of BiomarkerPrognostic
CohortSamples from 13 BPH patients (controls), 11 patients with localized PC (LPC), 9 patients with lymph node metastases (N1) or distant metastases (M1), and 11 patients with castration resistant PC (CRPC) were selected
Senstivity25%
Specificity100%
AUC0.735 (95% CI: 0.562-0.908)
AccuracyNA
Level Of Significancep=0.028
Method UsedmiRCURY LNA microRNA PCR
ClinicalNo
RemarksSpecificity fixed at 100%, sensitivity is calculated accordingly; Disseminated Disease include N1, M1 and CRPC
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA