CTYPE html> ProCanBio | Biomarker Card

Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID19
PMID14654526
Year2003
BiomarkerXLKD1/LYVE1
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationDownregulated in PCa(atleast 2 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysAngiogenisis
ExperimentNormal Prostate vs Prostate Cancer
Type of BiomarkerDiagnostic
Cohort14 patients with prostate cancer and 7 normal prostates were included for analysis
SenstivityNA
SpecificityNA
AUC0.061
AccuracyNA
Level Of Significancep<0.05
Method UsedqRT-PCR
ClinicalNo
RemarksOut of 291 genes, 46 genes showed differential expression, out of which a 4 gene panel was selected to differentiate b/w the patients who relapsed and those who did not.
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameLYVE1