Biomarker ID | 1899 |
PMID | 30611450 |
Year | 2019 |
Biomarker | MYC |
Biomarker Basis | Expression Based |
Biomolecule | DNA (Copy Number variations) |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Agressive PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Signal transduction, Gene expression, Interleukin-2 signaling pathway, Disease, Binding of RNA by insulin-like growth factor 2 mRNA binding proteins (IGF2BPs/IMPs/VICKZs) |
Experiment | Gleason Grade 4 in Gleason Score 7 |
Type of Biomarker | Prognostic |
Cohort | 124 patients, were chosen GS6 (n=41), large volume GS6 (n=26), GS7 (n=28), and GS8 and higher (n=29). |
Senstivity | NA |
Specificity | NA |
AUC | 0.90 (95% CI: 0.82-0.97) |
Accuracy | NA |
Level Of Significance | p<0.01 |
Method Used | fluorescence in situ hybridization (FISH) |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |