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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1899
PMID30611450
Year2019
BiomarkerMYC
Biomarker BasisExpression Based
BiomoleculeDNA (Copy Number variations)
SourceTissue
SubjectsHumans
RegulationUpregulated in Agressive PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: Signal transduction, Gene expression, Interleukin-2 signaling pathway, Disease, Binding of RNA by insulin-like growth factor 2 mRNA binding proteins (IGF2BPs/IMPs/VICKZs)
ExperimentGleason Grade 4 in Gleason Score 7
Type of BiomarkerPrognostic
Cohort124 patients, were chosen GS6 (n=41), large volume GS6 (n=26), GS7 (n=28), and GS8 and higher (n=29).
SenstivityNA
SpecificityNA
AUC0.90 (95% CI: 0.82-0.97)
AccuracyNA
Level Of Significancep<0.01
Method Usedfluorescence in situ hybridization (FISH)
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA