Biomarker ID | 1890 |
PMID | 30641210 |
Year | 2019 |
Biomarker | Interleukin 8 [SNP: rs4073 AA vs TT] |
Biomarker Basis | Mutation Based |
Biomolecule | Mutation |
Source | Blood |
Subjects | Humans |
Regulation | Ig heavy chain Vâ€III region BRO (0.1â€fold); Alphaâ€1â€antitrypsin (0.1â€fold); Plasminogen (0.1†fold); Ig heavy chain Vâ€III region TIL (0.1â€fold); Hemopexin (0.1â€fold); Afamin (0.1â€fold); Interâ€alphaâ€trypsin inhibitor heavy chain H1 (0.1â€fold); Protein AMBP (0.1â€fold); Alphaâ€1Bâ€glycoprotein (0.03â€fold); Complement component C8 alpha chain (0.06â€fold); |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 0.42 (95% CI: 0.24-0.76) |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Benign Prostatic hyperplasia |
Type of Biomarker | Diagnostic/Prognostic |
Cohort | 530 individuals including 130 PCa patients, 200 BPH patients and 200 male controls were selected for the study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.002 |
Method Used | ARMS-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |