| Biomarker ID | 1890 |
| PMID | 30641210 |
| Year | 2019 |
| Biomarker | Interleukin 8 [SNP: rs4073 AA vs TT] |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | Ig heavy chain Vâ€III region BRO (0.1â€fold); Alphaâ€1â€antitrypsin (0.1â€fold); Plasminogen (0.1†fold); Ig heavy chain Vâ€III region TIL (0.1â€fold); Hemopexin (0.1â€fold); Afamin (0.1â€fold); Interâ€alphaâ€trypsin inhibitor heavy chain H1 (0.1â€fold); Protein AMBP (0.1â€fold); Alphaâ€1Bâ€glycoprotein (0.03â€fold); Complement component C8 alpha chain (0.06â€fold); |
| Odds Ratio/Hazard Ratio/Relative Risk | OR: 0.42 (95% CI: 0.24-0.76) |
| Effect on Pathways | NA |
| Experiment | Prostate Cancer Vs Benign Prostatic hyperplasia |
| Type of Biomarker | Diagnostic/Prognostic |
| Cohort | 530 individuals including 130 PCa patients, 200 BPH patients and 200 male controls were selected for the study |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.002 |
| Method Used | ARMS-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |