Biomarker ID | 1889 |
PMID | 30641210 |
Year | 2019 |
Biomarker | Interleukin 8 [SNP: rs4073 A vs T] |
Biomarker Basis | Mutation Based |
Biomolecule | Mutation |
Source | Blood |
Subjects | Humans |
Regulation | Isoform 2 of Eukaryotic translation initiation factor 2â€alpha kinase 4 (4 fold); Keratin type I cytoskeletal 10; SCOâ€spondin (10 fold); Serum amyloid Pâ€component (4 fold); Apolipoprotein(a) (4 fold); Keratin, type I cytoskeletal 9 (3 fold); Ig kappa chain Vâ€IV region (2.4 fold); Isoform 2 of Filamin A (2.4 fold); Keratin, type II cytoskeletal 1(2.6 fold); Keratin, type II cytoskeletal 2 epidermal (2.3 fold); |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 0.62 (95% CI: 0.46-0.84) |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Benign Prostatic hyperplasia |
Type of Biomarker | Diagnostic/Prognostic |
Cohort | 530 individuals including 130 PCa patients, 200 BPH patients and 200 male controls were selected for the study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.002 |
Method Used | ARMS-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |