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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID187
PMID16618727
Year2006
BiomarkerMMP9 (Matrix Metallopeptidase 9) [MMP9 1185]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- Syndecan 1 pathway,Gastrin pathwayUrokinase-type plasminogen activator (uPA) and uPAR-mediated signaling,TWEAK signaling pathway,Endochondral ossification
ExperimentCancerous Tissue Vs Normal Tissue
Type of BiomarkerDiagnostic
CohortTwo sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significance0.00262
Method UsedRT-PCR and qPCR
ClinicalNo
RemarksBrackets indicate ISOFORMS of the mRNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameMMP9