Biomarker ID | 1859 |
PMID | 30374275 |
Year | 2018 |
Biomarker | PDGF-BB/Cr (Platelet Derived Growth Factor-BB/creatinine) |
Biomarker Basis | Concentration Based (ng/mg) |
Biomolecule | Protein |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated in Recurrent PCa |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 1.04 (95% CI: 1.01-1.08) |
Effect on Pathways | Pathway include: RET signaling; Apoptotic Pathways in Synovial Fibroblasts; GPCR Pathway; PI3K/AKT activation; ERK Signaling |
Experiment | Prostate Cancer Vs No Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | 118 patients were chosen for analysis in this study |
Senstivity | 67.5% |
Specificity | 52.6% |
AUC | 0.6362 |
Accuracy | NA |
Level Of Significance | p=0.016 |
Method Used | ELISA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |