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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID185
PMID16618727
Year2006
BiomarkerNME1 (Nucleoside Diphosphate Kinase A) [NME1 0827]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- Nucleotide di- and triphosphate biosynthesis and interconversion,Endocytotic role of NDK, phosphins and dynamin,,CDC42 activity regulation,, Arf6 integrin-mediated signaling pathway,E-cadherin nascent AJ-like junctions pathway
ExperimentCancerous Tissue Vs Normal Tissue
Type of BiomarkerDiagnostic
CohortTwo sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significance0.001945
Method UsedRT-PCR and qPCR
ClinicalNo
RemarksBrackets indicate ISOFORMS of the mRNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNME1