Biomarker ID | 1849 |
PMID | 30728149 |
Year | 2019 |
Biomarker | miR-30c-5p |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Urine |
Subjects | Humans |
Regulation | Differentially Expressed |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathway include: regulation of transcription by RNA polymerase II,; Gene expression (Transcription); cellular protein modification process; protein modification process; cellular metabolic process |
Experiment | Prostate Cancer Vs Benign prostatic hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | 4 cohorts were selected for analysis.Cohort 1 has 404 PCa, and 42 BPH, Cohort 2 has 99 BPH samples and 215 PCa samples, Cohort 3 has 148 BPH and 139 PCa samples, cohort 4 has 101 benign and 132 malignant samples |
Senstivity | NA |
Specificity | NA |
AUC | Cohort 1: 0.81; Cohort 2: 0.69 |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |