Biomarker ID | 1835 |
PMID | 30616540 |
Year | 2019 |
Biomarker | SRD5A2 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 0.9 (95% CI: 0.786–1.021) |
Effect on Pathways | Pathways include: Steroid hormone, vitamin A, and vitamin D metabolism, Steroid hormone biosynthesis, Prostate cancer, Lipid and lipoprotein metabolism, Androgen biosynthesis |
Experiment | Biochemical Recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | 158 patients from TCGA were taken into account for this study who had Gleason Score 7. 13 patients experienced Biochemical Recurrence |
Senstivity | 80% |
Specificity | 88% |
AUC | 0.884 |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | RNA-Seq |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |