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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1830
PMID30616540
Year2019
BiomarkerE2F2
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskOR: 2.84 (95% CI: 0.715–11.309)
Effect on PathwaysPathways include: Pathways in cancer, Cell cycle, TGF-beta regulation of extracellular matrix, Interleukin-2 signaling pathway, Cyclin D-associated events in G1
ExperimentBiochemical Recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort158 patients from TCGA were taken into account for this study who had Gleason Score 7. 13 patients experienced Biochemical Recurrence
Senstivity77%
Specificity63%
AUC0.682
AccuracyNA
Level Of Significancep<0.05
Method UsedRNA-Seq
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA