Biomarker ID | 1811 |
PMID | 30926382 |
Year | 2019 |
Biomarker | PHI (Prostate Health Index) |
Biomarker Basis | Concentration Based |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs No Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | 221 patients were included in the study. 129 were non cancerous and 82 were cancerous. 121 patients underwent nonfused biopsy and 90 had fused biopsies |
Senstivity | NA |
Specificity | NA |
AUC | Non Fused Biopsy: Univariate: 0.78 (95% CI: 0.67-0.88); Multivariate: 0.79 (95% CI: 0.68-0.89)Fused Biopsy: Univariate: 0.70 (95% CI: 0.59-0.81); |
Accuracy | NA |
Level Of Significance | NA |
Method Used | NA |
Clinical | No |
Remarks | PHI: [-2]proPSA/fPSA x√PSA. Base Model includes: age, DRE, and prior biopsy |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |