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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1811
PMID30926382
Year2019
BiomarkerPHI (Prostate Health Index)
Biomarker BasisConcentration Based
BiomoleculeProtein
SourceSerum
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentProstate Cancer Vs No Prostate Cancer
Type of BiomarkerDiagnostic
Cohort221 patients were included in the study. 129 were non cancerous and 82 were cancerous. 121 patients underwent nonfused biopsy and 90 had fused biopsies
SenstivityNA
SpecificityNA
AUCNon Fused Biopsy: Univariate: 0.78 (95% CI: 0.67-0.88); Multivariate: 0.79 (95% CI: 0.68-0.89)Fused Biopsy: Univariate: 0.70 (95% CI: 0.59-0.81);
AccuracyNA
Level Of SignificanceNA
Method UsedNA
ClinicalNo
RemarksPHI: [-2]proPSA/fPSA x√PSA. Base Model includes: age, DRE, and prior biopsy
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA