| Biomarker ID | 18 |
| PMID | 10460196 |
| Year | 1999 |
| Biomarker | Insulin Like Growth Factor-1 (IGF-1) |
| Biomarker Basis | Concentration Based (ng/mL) |
| Biomolecule | Protein |
| Source | Serum |
| Subjects | Mice |
| Regulation | Downregulated in SPI (soy protein isolate) diet: [Control: (223 ±61ng/ml; SPI Diet: 349 ±40 ng/ml ) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Angiogenesis |
| Experiment | PCa Mice fed Control Diet Vs PCa Mice fed soy protein isolate Diet |
| Type of Biomarker | Prognostic |
| Cohort | 48 SCID mouse cells were divided into 6 groups. SPI ( Soy Protein Isolate) contained 5 mice, and Control Diet consisted of 4 mice. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | Radioimmunoassay |
| Clinical | No |
| Remarks | LNCaP human prostate cells were injected in mice to study affect of Soy. Control diet consisted of casein-based control diet. |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on human patient cohort |
| Technical Name | IGF1 |