Biomarker ID | 1764 |
PMID | 30324582 |
Year | 2018 |
Biomarker | miR-205 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Serum |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; positive regulation of cellular metabolic process; positive regulation of metabolic process; nervous system development |
Experiment | Prostate Cancer Vs No Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | 72 PCa patients and 34 healthy controls were used for analysis |
Senstivity | 77.78% |
Specificity | 100% |
AUC | 0.914 (95% CI: 0.860-0.967) |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | miR-205 cutoff: 0.668 |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |