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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1750
PMID30800682
Year2019
BiomarkerNeutrophil to Lymphocyte Ratio (NLR)
Biomarker BasisOthers
BiomoleculeOthers
SourceBlood
SubjectsHumans
RegulationUpregulated in PCa: Fold change mean(BPH: 1.470; PCa: 54.384)
Odds Ratio/Hazard Ratio/Relative RiskMultivariate: HR: 4.57 (95% CI: 1.31-15.96)
Effect on PathwaysNA
ExperimentOverall Survival Vs No Overall Survival
Type of BiomarkerPrognostic
Cohort106 patients with CRPC were selected for the study. Patients were divided into 2 groups on the basis of NLR. higher NLR group (≥2.14; n=71) and lower NLR group (<2.14; n=35). All patients underwent Enzalutamide treatment
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.017
Method UsedNA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA