Biomarker ID | 1750 |
PMID | 30800682 |
Year | 2019 |
Biomarker | Neutrophil to Lymphocyte Ratio (NLR) |
Biomarker Basis | Others |
Biomolecule | Others |
Source | Blood |
Subjects | Humans |
Regulation | Upregulated in PCa: Fold change mean(BPH: 1.470; PCa: 54.384) |
Odds Ratio/Hazard Ratio/Relative Risk | Multivariate: HR: 4.57 (95% CI: 1.31-15.96) |
Effect on Pathways | NA |
Experiment | Overall Survival Vs No Overall Survival |
Type of Biomarker | Prognostic |
Cohort | 106 patients with CRPC were selected for the study. Patients were divided into 2 groups on the basis of NLR. higher NLR group (≥2.14; n=71) and lower NLR group (<2.14; n=35). All patients underwent Enzalutamide treatment |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.017 |
Method Used | NA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |