Biomarker ID | 1748 |
PMID | 30250996 |
Year | 2018 |
Biomarker | miR-1274a |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Validated: PI3K_AT; Predicted: MAPK; Apoptosis; mTOR; P53;Cell cycle; |
Experiment | Prostate Cancer Vs Benign prostatic hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | Rretrospective study of 105 samples (86 PC samples and 19 controls) was performed. 71 had prostate cancer and 15 had Castration Resistant Prostate Cancer (CRPC) |
Senstivity | NA |
Specificity | NA |
AUC | 0.784 |
Accuracy | NA |
Level Of Significance | p=0.00001 |
Method Used | rt-QPCR |
Clinical | No |
Remarks | The fold change was calculated by the 2^(−ΔΔct* expression) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |