Biomarker ID | 1722 |
PMID | 30719174 |
Year | 2019 |
Biomarker | FOXM1 (Forkhead Box M1) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | Univariate: HR: 10.524 (95% CI: 1.400-79.087); Multivariate: 8.819 (95% CI: 1.166-66.711) |
Effect on Pathways | Pathway include: Regulation of PLK1 Activity at G2/M Transition; Cell Cycle, Mitotic; DNA Damage; Cellular senescence (KEGG); Cyclin A/B1 associated events during G2/M transition |
Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | Tissues were collected from patients with low (n=17), intermediate- (n=36), and high-risk (n=29) disease and from patients with CRPC (n=2) and from patients with BPH (n=28) |
Senstivity | NA |
Specificity | NA |
AUC | 0.807 (95% CI 0.719-0.894) |
Accuracy | NA |
Level Of Significance | Univariate: p=0.022; Multivariate: p=0.035 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |