| Biomarker ID | 1716 |
| PMID | 26238235 |
| Year | 2015 |
| Biomarker | TEP1 (Telomerase Associated Protein 1) [SNP: rs1760904 AA vs GG] |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | HR:Univariate: 0.55 (95% CI: 0.37-0.88); Multivariate: 0.51 (95% CI: 0.27-0.94) |
| Effect on Pathways | Pathway include: Apoptotic Pathways in Synovial Fibroblasts |
| Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
| Type of Biomarker | Prognostic |
| Cohort | 1015 PCa cases and 1052 cancer-free controls were selected for this process. Out of those who experienced BCR, 51 had GG genotype, 13 had AA and 49 had AG or AA. Out of those who did not experience BCR, 116 had GG, 57 had AA and 210 had AG or AA |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.032 |
| Method Used | RT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |