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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1708
PMID26126436
Year2015
Biomarkerhsa-miR-4316
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceTissue+Urine+Serum
SubjectsHumans
RegulationUpregulated in PCa (Tissue, Serum, Urine)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathway include: synapse; nervous system development; Golgi apparatus; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity
ExperimentProstate Cancer Vs Benign prostatic hyperplasia
Type of BiomarkerDiagnostic
CohortFor training cohort 99 PCa with 51 controls were selected. Tissue, Urine and Serum all three samples were analysed
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of SignificanceTissue: p<0.001; Urine: p=0.022
Method UsedqRT-PCR
ClinicalNo
RemarksValues in regulatation column are presented as median (interquartile range; × 102 copies/miRNA concentration)
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA